AICAR 50mg

THIS PRODUCT IS INTEDED AS A RESEARCH CHEMICAL ONLY.
This designation allows the use of research chemicals strictly in vitro for testing and laboratory experimentation only. All products information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professional. This product is not a drug, food or cosmetic and may not be misbranded, misused or mislabled as a drug food or cosmetic.

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide), also known as Acadesine, is a synthetic AMP analog widely investigated in metabolic and cellular energy research. Although commonly grouped with research peptides by suppliers, AICAR is technically a small-molecule AMPK activator rather than a peptide. It is extensively used in laboratory studies to explore AMP-activated protein kinase (AMPK) signaling, one of the body's primary regulators of cellular energy balance.

Once inside cells, AICAR is converted into ZMP, a molecule that closely resembles AMP. This interaction activates AMPK, initiating a series of metabolic responses that help cells adapt during periods of energy demand. Because AMPK regulates glucose uptake, fatty acid oxidation, mitochondrial activity, and cellular metabolism, AICAR has become an important research compound for scientists investigating metabolic health, exercise physiology, and mitochondrial function.

Researchers have utilized AICAR in numerous experimental models to better understand how AMPK influences energy homeostasis and cellular adaptation. Studies have explored its role in regulating glucose metabolism, improving mitochondrial efficiency, enhancing fatty acid utilization, and supporting cellular responses to metabolic stress. These characteristics have made AICAR one of the most frequently studied AMPK activators in modern biomedical research.

Interest in AICAR has expanded into several scientific disciplines, including metabolic disorders, obesity research, cardiovascular biology, skeletal muscle physiology, aging, and exercise science. Experimental investigations continue to evaluate how activation of AMPK may influence mitochondrial biogenesis, insulin signaling, oxidative stress, and cellular resilience under challenging physiological conditions.

Areas of Scientific Research

AICAR continues to be investigated in laboratory settings involving:

• AMP-activated protein kinase (AMPK) signaling
• Cellular energy metabolism
• Mitochondrial function and bioenergetics
• Glucose uptake and metabolic regulation
• Fatty acid oxidation
• Insulin signaling pathways
• Exercise physiology and endurance research
• Skeletal muscle metabolism
• Cardiovascular research
• Cellular stress adaptation
• Healthy aging and longevity research
• Metabolic disease models

Scientists continue to investigate these biological pathways to better understand how AMPK activation contributes to maintaining cellular energy balance and metabolic flexibility.

Product Quality

AICAR 50mg is supplied as a lyophilized (freeze-dried) powder, providing excellent stability for laboratory storage and scientific applications. The lyophilization process helps preserve molecular integrity during shipping and long-term storage while allowing researchers to prepare solutions according to their experimental protocols when needed. High-quality research material should undergo analytical verification for identity and purity using validated laboratory techniques such as HPLC.

For Research Use Only. This product is intended solely for laboratory research and analytical purposes. It is not intended for human consumption, therapeutic use, or veterinary applications.